Resistance to chemotherapy is a major reason that patients with the most malignant form of ovarian cancer do not have a good chance of survival. Now researchers have discovered a biomarker that should improve prospects for patients by indicating how their bodies are likely to react to ... Read More »
A one-two punch against ovarian cancer
With few symptoms and no screening tests, ovarian cancer can furtively spread before many women even know they have it. And although rare, it can be deadly. Only 1.3 percent of cancers diagnosed between 2004 and 2010 were cancers of the ovary, but fewer than half of these women survived for five ... Read More »
Hope for Early Ovarian Cancer Detection
By Erika Schwartz, M.D It’s been dubbed the “tampon test” — and it may soon prove to be the most reliable form of early detection for ovarian cancer. In a new study, researchers found tumor DNA in tampons from women with advanced-stage ovarian cancer, offering proof, they say, that genetic ... Read More »
Researchers pinpoint two genes that trigger severest form of ovarian cancer
In the battle against ovarian cancer, UNC School of Medicine researchers have created the first mouse model of the worst form of the disease and found a potential route to better treatments and much-needed diagnostic screens. Led by Terry Magnuson, PhD, the Sarah Graham Kenan Professor and chair ... Read More »
New drug treatment beating ovarian cancer
A new type of intensive chemotherapy is proving highly effective in treating women desperately ill with ovarian cancer, scientists announced today. The pioneering treatment is successful in 80% of patients whose first-line chemotherapy had failed, compared to rates of less than 15% under current ... Read More »
Cancer-killing virus plus chemotherapy drug might treat recurrent ovarian cancer
In six out of 10 cases, ovarian cancer is diagnosed when the disease is advanced and five-year survival is only 27 percent. A new study suggests that a cancer-killing virus combined with a chemotherapy drug might safely and effectively treat advanced or recurrent forms of the disease. Researchers ... Read More »
Ovarian cancer: Know your body, know your risk
Ovarian cancer is the fourth leading cause of death in American women, with about 22,000 diagnosed and 14,000 dying from the disease each year. September is Ovarian Cancer Awareness month and Mount Sinai experts are sharing tips on prevention. "There is no effective surveillance technique for the ... Read More »
Researchers identify priority targets for immunotherapy in epithelial ovarian cancer
Researchers at Roswell Park Cancer Institute (RPCI) have found that the expression pattern of a unique class of tumor-associated antigens, known as the MAGE cancer-testis antigens (CTAs), correlates with clinical outcome in epithelial ovarian cancer. Based on their findings, the researchers have ... Read More »
Breakthroughs made in ovarian cancer research
Scientists at A*STAR's Institute of Medical Biology (IMB) and the Bioinformatics Institute (BII) have found new clues to early detection and personalised treatment of ovarian cancer, currently one of the most difficult cancers to diagnose early due to the lack of symptoms that are unique to the ... Read More »
Ovarian cancer cells more aggressive on soft tissues
When ovarian cancer spreads from the ovaries it almost always does so to a layer of fatty tissue that lines the gut. A new study has found that ovarian cancer cells are more aggressive on these soft tissues due to the mechanical properties of this environment. The finding is contrary to what is seen ... Read More »